Microdetermination of Urinary Hippuric and Methyl Hippuric Acid on Toluene and Xylene Poisoning
نویسندگان
چکیده
منابع مشابه
Urinary hippuric acid concentration after occupational exposure to toluene.
The results of industrial investigations have shown a correlation between the rate of hippuric acid excretion in a single urine sample collected after daily occupational exposure and the amount of toluene absorbed. The rate of hippuric acid excretion and the average concentration of toluene vapour during exposure time were also related. The quantitative range of the test has been limited to amo...
متن کاملToxicokinetics of toluene and urinary excretion of hippuric acid after human exposure to 2H8-toluene.
Nine male volunteers were exposed to 2H8-toluene (200 mg/m3 for two hours during a workload of 50 W) via inspiratory air with the aid of a breathing valve and mouthpiece. Labelled toluene was used to differentiate between hippuric acid originating from exposure to toluene and hippuric acid normally excreted in urine. The total uptake of toluene was 2.2 (standard deviation (SD) 0.2) mmol, or 50%...
متن کاملUrine Methyl Hippuric Acid Levels in Acute Pesticide Poisoning: Estimation of Ingested Xylene Volume and Association with Clinical Outcome Parameters
To determine the relationship between the oral ingestion volume of xylene and methyl hippuric acid (MHA) in urine, we measured MHA in 11 patients whose ingested xylene volume was identified. The best-fit equation between urine MHA and ingested amount of xylene was as follows: y (ingested amount of xylene, mL/kg) = -0.052x² + 0.756x (x = MHA in urine in g/g creatinine). From this equation, we es...
متن کاملUrinary hippuric acid and orthocresol excretion in
ABSTRACr It is not known whether urinary excretion of hippuric acid (HA) or orthocresol (0-Cr) is to be preferred for the biological monitoring of workers with occupational exposure to toluene. To study this, 42 printing trade workers with more than 10 years' exposure to a mixture of organic solvents including toluene (0-20 ppm) and 43 control subjects matched by age, smoking habits, and living...
متن کاملUrinary hippuric acid excretion in everyday life.
The biological monitoring for exposure to toluene is based on the measurement of urinary hippuric acid concentration (HA-U). In occupational health, workers exposed to toluene are examined for HA-U, because collection of urine samples is easy. The HA-U of some designers in a great household electrical products corporation who did not use toluene occupationally showed relatively high values. Fro...
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ژورنال
عنوان ژورنال: Sangyo Igaku
سال: 1964
ISSN: 0047-1879,1881-1302
DOI: 10.1539/joh1959.6.3_184_2